Ceva Thiazine 100 Injection

Thiazine 100

Active Constituent : 100mg/ml XYLAZINE (as hydrochloride)
Analgesic, Sedative and Muscle Relaxant for Use in Horses

Pharmacology : Xylazine is a non-narcotic sedative, analgesic and muscle relaxant
A therapeutic response may be expected in 1-5 minutes following intravenous administration.
A period of sedation is maintained for 1-2 hours, while significant levels of analgesia last 15-30 minutes. The Duration and depth of analgesia and sedation are dependant on dose and temperament.
Intravenous administration reduces heart rate and respiratory rate and may produce transient heart block.

Indications:
1. Radiography : Tp Calm alarmed or Difficult animals so they remain immobile during radiography.
2. Diagnostic Procedures : To Keep the animal calm and quiet during mare painful diagnostic procedures; Endoscopy, Ophthalmic examination, Rectal examination, peritoneal tap.
3. Minor Surgical Procedures : Suturing, Bandaging, Surgery under local anaesthetic
4. Anaesthesia : In Combination with ketamine to induce anaesthesia.
    Post-anaesthesia to smooth difficult recoveries.
5. Colic : Horses with severe colic frequently become unmanageable and in danger of serious Self-injury. Thiazine 100 can be an effective analgesic/sedative in case of spasmodic (hypermotility)colic and has the capacity to facilitate further examination and reduce the risk of injury to handlers and animals. however, its use is contraindicated in case of obstructive colic or ileus (see Contraindications Below) and therefore considerable care should be taken in diagnosis especially in the early presentation of colic as it may be difficult to differentiate between spasmodic colic and one that may progress to obstructive colic and alternative analgesia may be more appropriate if diagnosis is in doubt.

DIRECTION FOR USE:

Contraindications
This Product is contraindicated in the following situations:
- Intra-arterial administration
- Use in horses with Obstructive colic or ileus
- Use in mares in last trimester of pregnancy
- Concurrent administration with adrenaline

Precautions
Not recommended for use in animals with cardiovascular or cardiac disease, shock hypotension or hypertension.
Avoid use with tranquilisers or other agents that may gives rise to cardiovascular effects.
Not recommended for use in animals with respiratory depression. because xylazine may cause muscle relaxation of the upper respiratory tract, take particular care if an animal shows pre-existing signs of upper airway obstruction.
Avoid use in animals with renal or hepatic disease.
Avoid painful stimuli which may cause an apparently sedated animal to suddenly react without restraint. Sedated animals may also react unpredictably to noise.
Exercise due caution when handling xylazine-sedated horses which may become hyper-sensitive to touch around the hindquarters. Such horses may lick.

Dosage and Administration:
Horse : Mild sedation
Intravenous (slow): 0.25-0.5 ml per 100kg BW(0.25-0.5 mgper kg).

Heavy sedation
Intravenous (slow): 1.1 ml per 100kg BW(1.1mg per kg)
Intramuscular : 2.2ml per 100kg BW (2.2mg per kg).

Any unused portion of product should be discarded 3 months after first broaching the vial.

Meat Withholding Period
(Horses): 28 Days.

First Aid : If Poisoning occurs, contact a doctor or poisons information centre

Disposal : Dispose of empty container by wrapping with paper and putting in garbage.

Storage: Store below 25°C (Air conditioning). Protect from Light.

Read Enclosed Leaflet Before Using This Product.

Size : 50 ml